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Gap Junctions in the Brain | Zookal Textbooks | Zookal Textbooks
  • Author(s) Ekrem Dere
  • SubtitlePhysiological and Pathological Roles
  • Edition1
  • Published30th August 2012
  • PublisherAcademic Press
  • ISBN9780124159013

Physiological and Pathological Roles

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.

Gap Junctions in the Brain

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  • Author(s) Ekrem Dere
  • SubtitlePhysiological and Pathological Roles
  • Edition1
  • Published30th August 2012
  • PublisherAcademic Press
  • ISBN9780124159013

Physiological and Pathological Roles

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.
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